Bitcoin is the only one I have faith in currently. It has merchant adoption behind it and media attention whereas alts don't. They're just essentially for people who missed the bitcoin boat and want to try find the next NXT big thing.
BTC? Anonymouse developer has left, community takeovers always do fail. Heavily, with a THUD!
There's a premine bag left that could get dumped anytime.
High inflation due to daily miner dumping. Prise falling now all year long. Willybot pump from Gox is over, it seems.