If you are serious about building an operation at the scale you mentioned earlier you could certainly improve your power choices, you are taking a capital and 10-15% efficiency hit with what you choose.. If you are going to scale it up there are much better options...
That's an excellent point.
I'm going to look at the PSUs that I already have, but more efficient choices could make a big difference at this scale. A 100w difference per PSU would add up to 12,000W diff at the end.