Coinbase, becauae
-Great volume,
-Great customer service,
-Good reputation
Both you and op should read this
http://www.theverge.com/a/anatomy-of-a-hackCoinbase may have some atributes that make it good, but security is not one of them judging by this story. This is exactly why im using btc-e, even tho they also have
few issues (hard to get funds credited,slow response from support etc.)
cheers