Also we are about to expand our neural cortex into the cloud, and increase the size of the neural cortex a thousand fold (and then again) there is no telling what will happen. The last time we did this as a species, we invented, language, mathematics, agriculture, french, art, music etc etc...
The world is going to change more in the next 50 years than in the last 100-200, and in the next 100 years as much as in the past 500.
The only thing that will stop this is, nuclear war, plague or heat death.
I'm pretty sure those qualify as 'change'...
Good one!

Yeah my dog changed when it died.

(when I think of it , humanity , or homo-sapiens may change more in the next 100 years than they have in (insert very large number here) amount of years... 500 years may not be a big enough number, you could say that as soon as super augmented intelligence, and AIs with the capacity of 1000 times the entire human races brain power, and virtual immortality, become a reality, that we would have transcended what we now call human)
It's life Jim, but not as we know it.