It isn't hard to create a new address for each transaction is it? better to be safe than sorry!
I don't see how this provides much extra security. If you access wallet each time and it has all these addresses, I don't think it matters if compromised.
I think security is more about your wallet then amount of address's you use.
It covers a far more obscure and rare risk vector but it's more about privacy. You might be tripped up further down the line if every single transaction can be traced to you. And I guess if you're changing your address it'll inspire you to take your security elsewhere more seriously.