How about exchange sites, shopping sites, cloud mining sites, altcoins, or any other type of sites/services which deals in bitcoins because one has to send bitcoins to them for one thing or the another?
Are they safe?
As a general rule of thumb,
NO!!!!!It's all a risk from the moment you turn real money into bitcoin.
I trust Coinbase and Cryptsy, that's about it. I just crossed Poloniex off the list earlier this week. So now we're down to 2 entities. And I don't really even trust Cryptsy that much.