Hi,

inevitably some coins will be lost - broken laptops, irrecoverable wallets etc. Same as losing real coins under the sofa.
As there is a limited number of coins (presumably these won't be replenished), then in effect we have an ever dwindling supply of coins.
Over time the supply will just get less and less. 21 million isn't a huge number of coins.

Would this be an additional factor to cause the price to increase?