Best way is gambling. I turned 0.6btc into 40btc in 4 months.
for everyone that is lucky enough to do this, there are ten who have lost 4 btc, not what i would call the best investment
usually the best investments is the one with the highest profit and the lowest risk(the best ratio between those two), gambling isn't one of these, because it has 1:1 ratio
i can't see much , besides shorting or investing in some hyip, there is also altcoin, but they are even more dangerous,
otherwise you can try with some services that offer a loan system, but those are also far away from being free of risks
I am seriously against altcoin investments as they are barely profitable. The best you can earn from altcoin investment is when you buy altcoins as soon as they hit an exchange, buy as much as you can at that point of time

there are some pump groups, if you can follow those closely and be ready when they start to pump something, money are guaranteed
i found this for example, yesterday they pumped ktk
http://fairpumps.net/blockchain-pumps/ by 300% or around that