Space-time refers to a 4D space. Entropy knows no such limit in dimension. It is dimensionless and occupies all dimensions simultaneously. Choose your illusion (space) frame-of-reference.
Do you care to elaborate on the nature of (your) "[e]ntropy" (TPTB_need_war) as it exists to a Hilbert space (which is the space of this universe as it is modelled in "Cosmology from Quantum Potential")?