Choose one wallet and stick to it except if a change that you don't like appears.
Bitcoin core- For developers and people who care about security as bitcoin core verifies the entire block. It does take more space though.
SPV clients (MultiBit/Electrum)- For normal users, SPV client is usually enough and is ideal for people with smallish storage space. The security is not to the standards of Bitcoin core though.
What do you mean "The security is not to the standards of Bitcoin core though." ?