With Amla gone, I believe India will be the favourites.
They just have to keep chipping away.
Yes Amla wicket would be big hope for India to win this test. But South Africa aim for historic blockathon to draw this match. They have quality batsmen to do so. So, I guess still there are chances for draw as well as for India winning.
If South Africa draw this test match, that would be new record. I do not think that is possible for them in India pitch. The new ball has been taken, that would be the new beginning for India hope to win this match to white wash South Africa 3-0 in this series.
But there are lot of chances for South Africa to create new record of playing many maiden overs to draw this match. India bowling is missing the fire works to force the batsmen to make mistakes to get out. So, South Africa dominates now towards a draw.