#p2pool uses twisted, and twisted uses zope.interface, and in order to install either one you need setuptools, so let's start with that:

wget https://bootstrap.pypa.io/ez_setup.py -O - | sudo pypy
sudo rm setuptools-18.3.2.zip

#Then zope.interface:

wget https://pypi.python.org/packages/source/z/zope.interface/zope.interface-4.1.3.tar.gz#md5=9ae3d24c0c7415deb249dd1a132f0f79
tar zxf zope.interface-4.1.3.tar.gz
cd zope.interface-4.1.3/
sudo pypy setup.py install
cd ..
sudo rm -r zope.interface-4.1.3*

#Then Twisted:

wget https://pypi.python.org/packages/source/T/Twisted/Twisted-15.4.0.tar.bz2
tar jxf Twisted-15.4.0.tar.bz2
cd Twisted-15.4.0
sudo pypy setup.py install
cd ..
sudo rm -r Twisted-15.4.0*