It is not like House always win. I've seen some aspiring new casinos gone bankrupt because couple lucky patrons killed casino's funds. Casino bankruptcy certainly can happen.
There are no casino that has been bankrupted yet if all players dont cheat the game. There are house edge to safe guard the casino so it wont fail in long term and will keep on generating profit. The only thing that you can do to make a casino bankrupt is either to steal (hack) or find some exploit to empty the bankroll