Let's start this by making myself a little less popular, saying: the altcoin scene will die in 2016
It is quite possible that the altcoin market will be devasted by a potential decline of Bitcoin to < $150 and perhaps well below $100, because we have an unexpected global contagion coming that will be worse than 2008 when everything crashed. As we all know, when Bitcoin's price gets a flu, altcoins' prices go into comas.
Coins that offer unique decentralized services, "Blockchain 2.0" or other disrupting technology will be the buy-and-holds for 2016. Some examples?
- Ethereum | Decentralized software & smart contracts on the blockchain - Factom | Honesty to record-keeping - Voxelus | Virtual Reality without coding - Radium | Decentralized Services on the smartchain - MaidSafe | Crowd-sourced internet - Synereo (AMP) | Decentralized social network - Sia | Decentralized storage
All those coins are doomed to fail due to insoluble fundamental technological issues which they didn't solve which render those coins entirely useless: