I find more one issue when I try to send transaction.
Can't send transaction with Ledger when "Use change addresses" in settings is unchecked.
I like to use the same address for change of transaction to consolidate bitcoins in one address but with Ledger this is impossible.
Give me error "Multiple outputs with no change not supported"
I report this issue here https://github.com/spesmilo/electrum/issues/1679