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Highest Ive seen someone win was over 1btc on a 1250x multiplier, he also has also hit that multiplier over 10 times now.
Edit:he has hit it 10 times.
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i don't believe this unless i see it with my own eyes.
on 1250x you have a 0.07% chance to win. which is 1 win in every ~1500 rolls besides there is no guarantee to win even if you roll 1500 times so he must have played for thousands of games to win 10 times which means no profit because you will lose the same amount in those thousands of rolls combined.