Only issue is more zeros after the decimal as it either becomes expensive or spread thinner. Guess the latter would also stimulate increase in price.

If you need to buy a magazine for .00000234 it could become a issue of the people adding or subtracting a zero to rip off or by mistake.
Recall preauthorizing credit cards so people could rent game consules at blockbuster back in the day.
Once locked a lady up for 1k instead of the normal 100. The zeros will be a hinder, hopefully we create a workaround for that if the time comes.