What % you sell depends on your risk tolerance and initial investment. For example perhaps you sell 50% after the price doubles, then you'll have your money back and hold half of your current moneroj.
I think a good way to go about it is to decide on the amount of XMR you want to own long term and then buy more, perhaps 2x what you want to own. Then you diversify as the price goes up until you have sold the exceeds, recovered your initial investment and still hold your preferred long term position.

That part is easy enough. Every time I try, the bar just raises with my buys though, and I never amass more than I want to hodl. Not sure where this ends. nioc's defective sell button seems to have infected my system. Perhaps I can free it up by
buying more. I should just buy on margin, then I have to sell eventually

TheKoziTwo, thank you very much for your posts. Always great perspective.
I don't have the means to take this advice of yours. I have built my Monero house brick by brick over the last 2 years partly by being more frugal than TC. I have had some rough financial times. Yet when somebody asks, "how are you?" I respond, "never better" because it's true. Happy Thanksgiving.