Is stratum+tcp://stratum.kano.is:3333 the best port for me to use if I live in Indiana U.S.? Does it matter as far location? I seen someone else ask that question a few pages back but I believe he was in Europe somewhere.
I've used all the nodes, and have settled on the link you have defined. I live in Hawaii. Ping time can be relevant, but I've found the port you're using to be stable and productive. I have a couple of friends who are in the US (West and Midwest) who have the same experience.
I'll second that. I'm in California and that's the main node I use, rarely fails over (to the solo pool, of course!!)