I don't think there is much difference based on where you live.

although I can tell you that if you live in Africa and willing to start a new business and deal with some problems that come with that, you can have a very good chance of making a very successful business in your country or city if there is no other place that works with bitcoin.

running a bitcoin exchange service accepting local currency, a bitcoin ATM, or many other things that don't exist in your country can be very good options