I think there is no difference if you sold big amount or small amount , because the fee doesn't change according to the amount you sell . For example : if you sold 1 BTC , the fee is 0.002BTC , and if you sold 0.1BTC ten times , the fee won't change .
yes fees doesn't change according to amount user sells but there are some exchanges that gives discount to users on trading fees based on their past trading volume.