It matters when you bought in the 1k+ range
No. It matters even with small holdes. Why not? Even if you just have 1btc once every dollar changed there is also an impact to you. Even lower than that you will feel it. I got like 3 million satoshis in one website exchange and yet I still feel the changes in its price.
When we have a volume of bitcoins, we will really feel even with a small price changes, like if we are trading, if we have a good capital, we are already happy if we even hit a 1% profit in a daily basis. Therefore, the price really matters for those people who having a business online.