Well never say never but right now its not good to sell your bitcoins because it still has a whole future a head and it can jump in price significantly, due to that I think its better to hold on right now.
Every time that you can see profit it is good to sell your bitcoin since we are here to have income why you do not sell if you can gain profit in the price of bitcoin, you do not sell your coins if the price is too low base on the price at the time of your investment.