The coin that reaches furthest past the speculative trading hub of bitcointalk will be the first coin after btc to surpass 1billion.
There isn't enough money here to make that happen.
XRP and Ether are the coins making progress. Right now cyptoenthusiasts are simply trading value but in order for the pie to grow significantly there will need to be an influx of fresh capital. My guess is that the new capital will come via XRP or Ether. more like XRP given that it's being actively integrated into the existing financial ecosystem. Ether will require the development and proliferation of desirable applications which have yet to be developed. Although I'm hopeful that Chronicled Inc. and other Ethereum platform-based services/products will start to gain traction soon.