yes there is no doubt about this that loans are too risky so you should be careful when taking loan as there is always a chance of loosing bitcoins if he price fell down so try not to buy or do trading on loans as you will then not be able to return it back.
what is the risk in taking a loan

the risk lies for the individual giving out the loan ,doing trade and gambling with loaned amount is a very risky thing as you never know when you are going to loose everything,bitcoin and price really never matter if you are not looking for a profit every month.
Most people who requests for the loan actually attempt to use in those aspects you mentioned just to make quick profit for which they are not sure of making. It is highly risky to take loan and just venture into gambling with. Better if you are taking loan use it for guaranteed investment with higher returns in order not to put yorself into financial trouble that can make your life very uncomfortable.