The Ledger Nano S can be restored from seed directly input on the device itself. That means there is no possibility of malware stealing your seed if you have to restore your wallet. The Nano S also stores private keys for Ether and Ether Classic, as well as Litecoin. It can be used for secure login on U2F sites like Google and Dropbox. More coins will probably be added. Nano S is just a giant step forward from the Nano so why save a few bucks. Get the better wallet. Your money your decision.
I don't anticipate owning enough altcoins to worry about storing them in a hard wallet, and I do not want to use my USB bitcoin wallet to login to websites. You make a good point about restoring the wallet from seed. The Nano would require using a safe or air-gapped computer which is less convenient. Nevertheless, the Nano seems more secure to me if initialized on a safe computer...and if their Android app works well.