There might be spikes, but it should be a problem for standard design cards. However, I am also experiencing this problem although I own RX480 ASUS Strix version using 8 pin power cable instead of 6 which is shipped on the standard design, and I also have a decent PSU which is Corsair 1200W (with gold certification) nevertheless, problem persists. Also -nofee 1 option is not helpful.
You will have to reduce the frequency of the core. The cores are stressed more. So it is quite unstalbe at present.