No, day 3.  The block reward is already 50.

Let's play calculate the premine!

1 block/min

First 24 hours, 1440 blocks at 500 mincoin each = 720,000
Next 24 hours, 1440 blocks at 100 mincoin each = 144,000

Only 10 million mincoins will be made

How generous of the authors to give themselves almost 10% of the total money supply in the first 48 hours!