Oh, wow, lucky you, what a nice hash power you have! So then it makes sense to solo mine with all your GPUs. Generally, Nexus GPU solo mining is worth when your total hashrate is higher than 100MHs (which will be no problem at all with your hw).
Is that better from Zcash in pool?
I don't know. But I think there are more profitable coins for GPU mining than Nexus right now. With all the power you have, I should rather go for Zcash or Monero pool mining and then buy Nexus as an investment.