Doing some research on the statistics, it appears that the Isoniazid is as likely a cause of the fatigue, and I must take that for another 19.5 weeks:
http://factmed.com/study-ETHAMBUTOL-causing-FATIGUE.phphttp://factmed.com/study-ISONIAZID-causing-FATIGUE.phphttp://www.ehealthme.com/ds/isoniazid/exhaustion,%20fatigue,%20lethargy,%20tiredness,%20weariness/The recommendation is to take it before bedtime to try to sleep through the fatigue:
Fatigue Usually due to INH. Take medicine about 2 hours before bedtime
so can sleep through the symptoms.
I hope my TB is not MDR because it requires up to 2 years of injections and very horrible antibiotics at very extreme doses:
https://drtbnetwork.org/37-duration-mdr-tb-treatmentAnd diagnosing MDR and confirming negative culture in extra-pulmonary TB and my likely Peritoneal TB can be much more complicated:
https://drtbnetwork.org/110-diagnosis-extrapulmonary-mdr-tbMy pulmonary TB was only in left lung and very minimal on my xray, yet my ongoing symptoms over the past years indicate it had disseminated into my gut.
The research I did shows a 14.3% incidence of MDR to Isoniazid and Rifampicin in the Philippines in terms of hospital admitted active cases. And for Polyresistance to Ethambutol and Pyrazinamide is roughly 0.5% in the Philippines. The thing is that I was exposed to a lot of filipinos over the years, so it is possible I could have been infected more than once, so then I don't know to what extent the odds of my having a MDR strain that really requires I pursue a MDR treatment regimen.
Also I am somewhat confused as I had originally thought that if resistance to Isoniazid and Rifampicin was found but not resistance to Ethambutol and Pyrazinamide, then the four drugs would be prescribed, but apparently I am reading now that instead must do the injections regimen! Ughh. Yuck.
So really we have no assurances that I am near the end of this. I might be in for a horrible fight over a couple of years.
So I really need to find some way to become productive while under treatment.
I also really need to earn enough money to get proper Western quality diagnostics in terms of a CT scan and then samples taken and cultures done, to determine the progress of treatment and whether I have a MDR strain. None of this I can afford. I have no health insurance.
A group of guys offered to fund my health care in a return trip to Singapore, but I was so sick in January so I decided to initiate treatment immediately. I thought that it was impossible to culture for drug susceptibility after initiating treatment, but apparently follow up cultures can also help determine treatment progress but I am not confident that culture negative from my lung is a negative for my gut and we have no baseline culture from the gut before initiating treatment. This is complicated now. I feel improved on current treatment regimen other than the fatigue which is preventing me from working, but that doesn't mean I don't have MDR strain and couldn't suffer relapse after finishing the next 19.5 weeks of treatment.
I probably need to follow up in Singapore or other Western country. I wasn't totally comfortable with accepting funds from those guys, although I appreciate the offer. I am confused as to what I should do now. But I will probably try switching my dosage from the mornings to evenings and see if that improves my ability to work.