Yes the question is clear. Arbitrage techniques are applied in bitcoin trade. Do you have any problems when you try Arbitrage?
Are there things that negatively affect you? Are there any things that make you harm?
By applying it, I think it will be complicated especially if you are in the actual trading in the exchange sites you need to be active in monitoring the price in the trading platform. Once the price is getting down, then you get bought it in the high value because all of a sudden dumped was happened it can be called as worst or one of the disadvantage of arbitrage.