Hmm, what I think about this is that how can you make this fair for everyone? How can you make this into some kind of gambling game where you have to have some sort of way to make everything be based off chance. Maybe instead of a gambling game, you could make a real game based on your idea. There aren't many games that are based off bitcoins.
If stronger player will always beat weak one, it's not good. There will be a chance for weaker player to beat a strong one. But this chance will not be really big.
I think power is not the decisive thing here, luck and intelligence always help you win. Think of the story in fact, if you're an agile guy, you can win over some formidable but stupid guy. For gambling the same is true, the tactics will work. Conversely, if you have a lot of money, but you do not know how to use it, it will not be your money.