I don't want to rule anything out at this stage, but my main goal with Gringotts is to support reliable and trustworthy on/off ramps for other crypto currencies into and out of CK, and I want the option of market making for a number of coins, maybe from more than one depository, so my first priority will be ensuring sufficient M to cover that without too much risk of falling short. If things go well, and there is enough M to market make for other in-game items then that is something I would consider doing, and if the official Game depo opens up again then the liklihood of having the resources is a lot greater. Other players may choose to MM for particular in-game items, and I don't want to crowd other players out from those opportunities.
It's good to be cautious, but with +425 bil markka you've probably got enough to cover multiple depo currencies and a few key game commodities like CAN and HM02B100 now. The real sticking point is Zechariah - will he honour his debts, what happens to his game account, will he return as GM ?
He will return stronger than ever and it will be glorious.