I'm using the Biostar TB250-BTC. Getting 6 GPUs on it was relatively easy compared to some of the stories I've heard about other boards- so much so that I bought two more for my 2nd and 3rd rigs. However, I started having issues with windows 10 forgetting how to use the onboard LAN and since then I've been struggling to get more than one card working on SimpleMining. Haven't had much time to troubleshoot it so take that as you will. I'm pretty confident though that my issues are not motherboard specific. Probs just BIOS related.

At least I hope so.