Personally I think the next big thing is not going to be a coin but a service, there are already decentralized exchanges, but there are some problems with them, we need those problems resolved so we are not dependent on centralized exchanges anymore, exchanges have centralized bitcoin we need to do something about it and decentralized exchanges are the answer.
Yes probably platforms which can be custom modified for business needs.
Exchanges, Markets, Lending services..More is better!
The next big project like bitcoin is SONM the project that will replace PoW Check the thread at the ANN section
POW is still very popular, it is obsolete and bad and must be replaced, but at this situation is most popular..All coins that don't have support from miners are in start handicapped, POW greed is more than needed for network security.