Lack of GPUs prolongs profitability for those who already have them, or manage to get some.

 However, do keep in mind that NVidia makes GPUs too, and they are very profitable on most coins and can often beat AMD on hash/watt even where they lose on hash/$ (mostly ETH ETC and such, and the Cryptonight coins like XMR).

 For ZEC (which isn't the most profitable NVidia coin by far but is probably has the second most GPUs mining on it) NVidia is quite close on hash/$ (and might even WIN on some comparisons) WITHOUT FACTORING IN the current AMD "gouge" pricing.



 Funny part - folks have been pushing the Skein coins a lot, but I actually ended up making more on something else (that I'm NOT going to mention here, as it's fairly small and I don't want the profitability of it to get overwhelmed by a bunch of newbies or even one BIG farm jumping all over it).