@GabryRox  I am running 7 GPU's on a msi m5 z170. ran it on ethOS & nanopool didn't like nanopool
switched to Win 10 & nicehash had a ram problem went from 4 to 6 solved it. making 8 usd a day more on nicehash.
Runs perfect.
having said that I would suggest getting the Z270. if it was me.