The general rule of thumb when it comes to starting your own pool: If you have to ask the question, you shouldn't do it.
Yeah but everyone needs to start somewhere. I'm just looking to mine with multiple computers instead of one.
And unless you are meaning 1000's when you say multiple you are best off joining a pool. And even then you probably need to hurry. Not that it can't be done or that you can't find a block yourself, but it's very unlikely.