Hi,
Today when I wanted to add fifth GPU, didt recognised by system (MSI after burner and clymore 9.6).
I've changed riser slots several times but not working. This my current PCI-E slots setting:
1, 2 (main slot), 3, 6
Motherboard: Biostar TB-250 BTC
GPU: MSI 1070
OS: Win 10
Just went through the same.
Look at the device manager and see what it says. If there's a "VGA" device listed somewhere with a yellow warning triangle you can try to right click and select update driver. That made my windows find the last GPU's. Also a few reboots seems to make additional GPU's to appear.
I tried reinstalling the drivers and changed riser slots, but that did nothing - only the above helped me.