I run a full node at home. I don't think running a full node is for everyone, but it's not that bad. CPU usage is pretty low, disk usage is acceptable, and network traffic is not too bad. The initial syncing process takes forever, though.

We should be able to increase the base block size modestly at this time, in addition to SegWit (for various other benefits it offers), without risking much centralization of nodes. I know my (3-year-old) computer can easily handle it.

As has been pointed out in this thread, the more significant deciding power is with the miners. At this point, I'm way more concerned about the centralization of mining than I am about centralization of nodes. I would rather not have a vast majority of the hashpower located in a single country. What can be done about that?