Wow, this is huge and it would means someone very rich
may have sold all his Bitcoins.
Do you think this is something to worry about?

It definitely doesn't look like it was a transaction between his/her own accounts.
Why wouldn't this just be someone moving a ton of coins to another address to ensure they get their Bitcoin Cash like everyone else is doing?
There are no need to moving fund to ensure you will have BCC. Even casascius coin now have double coin inside if bitcoin fork into BCC and BTC
Some people ONLY moving their coin from exchanger that NOT SUPPORT BCC to own wallet, not to moving between wallet. And i am not sure that is exchanger wallet, its must be someone's cold wallet