That's practically impossible. If they happen to do so, it won't take much time for the US government to chase them down, where after that we'll run into the same drama again. But even if they do end up returning, only a total idiot will make use of an exchange being operated by the same BTC-E staff.
You are so westernized in your thoughts, its really getting awkward. Impossible because the big mighty USA put a picture on a domain? Many countries and individuals give a shit about USA and only because USA says everything is illegal, it doesn't mean it is. If they open up again, I bet 90% of the Russians will use them again. Why USA is imposing sanctions against Russia and Russia isn't bending over?