I think if you have an investment to keep just for gambling and only play with the profits you gain from investing then you can gamble for as long as you can and not have to worry about losing everything or foong broke. Who knows after a big win you could invest that and have even more gambling money to play with.
Of course, yes. I will play with my profit. There is nothing to lose with it since this is already your profit. But not all my profit, I will bet maybe 25% of it first and so on to have a longer play time. Not on an all in, and lose all.
Well there is something to lose but it is profits and if you strict and stick to just playing with profitable you could gambled forever and supply yourself the bitcoins you need to have a gambling as a hobby.