I think the problem you are having is because you can't mix hardware when mining. You can run multiples of the same card, but not two completely different cards. Sometimes even the same model card by different manufacturers is problematic.
That's not true. I'm running a 7970, a 5750 and a 5850 on the same mainboard with GUIminer. I have no Problems...

Oh, and my second rig ist running with a 7770 and a 5850 with GUIminer. Also no problems!