That kind of monstorous gain simply from buying and holding is likely not going to happen again.  It's clearly still possible to get "lucky" and hit 1000x level gains in rare situations and this year has had more than a few 100x opportunities. 

Personally I only have 3 holdings I consider LONG term (cold wallet, planning to leave alone for years.  Everything else I see as mid-term (within the year) or short-term (riding daily high/low).

I highly suspect the true bubble will burst as many of this years biggest ICOs are slowly unable to deliver on their promises and devalue substantially leaving many spec investors out money.  If/when that happens a lot of the easy money flowing in will dry up forcing sell-offs without the predatory buy-in recoupment we've been seeing this year.

It'll be much like the dotcom burst when the unicorn companies all started filing for bankruptcy.  A good lesson there though is even with NASDAQ being shredded in the late 90s a good number of companies survived and thrived and some savvy investors still did VERY well in tech over the following decade.