If it was just the amd driver failure then YES! I've found with my setup that if I enable and then disable crossfire it resets the driver if that is all that has crashed after playing with o/c settings.
I am referring to a case where the GPU gets locked up, and it is declared SICK/DEAD by cgminer.
Generally if the GPU is sick / dead that means the system survived an AMD driver reset already - hence the gpu stopped responding in CGMINER. I wrote a script in windows to restart cgminer if such a situation has occurred because, after restarting cgminer it continues mining w/ all GPU's once again.