i have reinstalled windows twice, updated and removed drivers 3 times, once using DDU.
reinstalled what windows ? 3.1 / 95 / 98 / 2000 / win 7 / win 8 / win 10 
updated and removed what drivers ?
I have tried everything i can damn think of and still at a loss to know what exactly is causing the problem. And was wondering if any one here has had this issue or knows whats wrong.
Give us a full system spec , including driver versions , windows version , what miner software are u using
Are u using powered risers ?
Can you check the widows error logs ( event viewer ) and post it here ?