Yes,

I only have 3 gpu's on in it now....

MSI GTX 1070 8BG
PNY GTX 1060 3GB
Zotac GTX 1060 6GB Mini

I am defiantly going to add more GPUS at some point.
I even have another Motherboard coming in this week to build a second rig.
But that is in the future maybe early next year.

Just got it up and running this is what I'm doing right now...
Nothing is overclocked. Dunno about all that stuff.

GPU0: 448 Sol/s GPU1: 268 Sol/s GPU2: 292 Sol/s
Total speed: 1008 Sol/s