I use different ones but mainly I use Electrum as a desktop wallet and for day to day use and spending.
I use the Ledger HW.1 hardware wallet as cold storage and to keep my majority of bitcoin safe from hacker attacks or different malware you can get in the internet.
Same, the ledger is like a physical safe for money, to secure them, and the Electrum resembles a regular wallet, in which you hold money for everyday operations