Do your homework, those with the best teams, product, roadmap, and funding have the best chance at success.
Here are my top five over the next 6- 9months, some of these will definitely be in the top 10 next year.
1. Waves
2. Civic
3. Golem
4. MobileGo
5. Tezos (would have this at 1. but the blockchain has not yet been created)